Whether it's a sequel to TP or not, a new Zelda game is always welcome. I'd rather it not be a motion-control game, but if it is, so be it.
Actually though I'd rather it be a different game and not a sequel. Twilight Princess was a pretty tired game with nothing overtly original...continuing off of that certainly doesn't open up a lot of doors. I'd like to see another cel-shaded Zelda game to make up for Wind Waker Link's image being ruined on the DS.
22 medium-jumbo frets, 3 mini humbuckers, 2 single-coil pickups, and 6 steel strings of pure sex.